Zyvox

Zyvox is used for:

Treating adults with certain serious bacterial infections that are often resistant to other antibiotics.

Zyvox is an oxazolidinone antibiotic. It works by interfering with the production of proteins needed by bacteria to grow.

Do NOT use Zyvox if:

• you are allergic to any ingredient in Zyvox
• you are taking an amphetamine (eg, dextroamphetamine), certain anorexiants (eg, phentermine), buspirone, a catechol-O-methyltransferase (COMT) inhibitor (eg, entacapone), levodopa, meperidine, a sympathomimetic (eg, albuterol, dopamine, epinephrine, pseudoephedrine), tetrabenazine, or triptans (eg, sumatriptan)
• you are taking or have taken certain anorexiants (eg, sibutramine), apraclonidine, bupropion, cyclobenzaprine, a monoamine oxidase inhibitor (MAOI) (eg, phenelzine), a norepinephrine reuptake inhibitor (eg, atomoxetine), a serotonin norepinephrine reuptake inhibitor (eg, duloxetine), a serotonin reuptake inhibitor (eg, paroxetine), a tetracyclic antidepressant (eg, maprotiline), or a tricyclic antidepressant (eg, amitriptyline) within the past 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Zyvox:

Some medical conditions may interact with Zyvox. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have a history of high blood pressure, kidney problems, bone marrow problems, low blood cell or platelet levels, an adrenal gland tumor (pheochromocytoma), carcinoid syndrome, severe liver problems, seizures, or an overactive thyroid
• if you have a prolonged infection that has been previously treated with another antibiotic medicine
• if you are taking any medicine for depression

Some MEDICINES MAY INTERACT with Zyvox. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Amphetamines (eg, dextroamphetamine), apraclonidine, certain anorexiants (eg, phentermine, sibutramine), ginseng, meperidine, sympathomimetics (eg, albuterol, dopamine, epinephrine, pseudoephedrine), or tryptophan because the risk of serious side effects, including severe headache, fever, or high blood pressure, may be increased
• Bupropion, buspirone, COMT inhibitors (eg, entacapone), levodopa, MAOIs (eg, phenelzine), norepinephrine reuptake inhibitors (eg, atomoxetine), propoxyphene, serotonin norepinephrine reuptake inhibitors (eg, duloxetine), tetrabenazine, tetracyclic antidepressants (eg, maprotiline), tricyclic antidepressants (eg, amitriptyline), or triptans (eg, sumatriptan) because the risk of serious side effects, including severe fever, mental or mood changes, or muscle problems, may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Zyvox may interact with other medicines that you take. C heck with your health care provider before you start, stop, or change the dose of any medicine.