Zocor

Zocor is used for:

Lowering high cholesterol and triglycerides in certain patients. It also increases high-density lipoprotein (HDL, "good") cholesterol levels. It is used along with an appropriate diet. It is used in certain patients to reduce the risk of heart attack, stroke, and death due to coronary heart disease. It is also used to reduce the need for medical procedures to open blocked blood vessels. It is also used in certain patients to reduce the risk of heart attack, stroke, blood vessel blockage, or chest pain caused by angina. It may also be used for other conditions as determined by your doctor.

Zocor is an HMG-CoA reductase inhibitor, also known as a "statin." It works by reducing the production of certain fatty substances in the body, including cholesterol.

Do NOT use Zocor if:

• you are allergic to any ingredient in Zocor
• you have liver problems or unexplained abnormal liver function tests
• you are pregnant or breast-feeding
• you are taking a macrolide antibiotic (eg, clarithromycin, erythromycin), an HIV protease inhibitor (eg, ritonavir), itraconazole, ketoconazole, mibefradil, nefazodone, or telithromycin

Contact your doctor or health care provider right away if any of these apply to you.

Before using Zocor :

Some medical conditions may interact with Zocor . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are planning to become pregnant
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have low blood pressure, kidney problems, diabetes, a serious infection, or a history of seizures
• if you have metabolism, hormonal, or electrolyte problems
• if you drink alcohol or have a history of liver problems or alcohol abuse
• if you have recently had major surgery or a serious injury

Some MEDICINES MAY INTERACT with Zocor . Tell your health care provider if you are taking any other medicines, especially any of the following:

• Amiodarone, certain azole antifungals (eg, itraconazole, ketoconazole), danazol, diltiazem, fibrates (eg, gemfibrozil, clofibrate), fluconazole, HIV protease inhibitors (eg, ritonavir), imatinib, immunosuppressants (eg, cyclosporine), macrolide antibiotics (eg, clarithromycin, erythromycin), mibefradil, nefazodone, niacin, non-nucleoside reverse transcriptase inhibitors (eg, delavirdine), risperidone, streptogramins (eg, dalfopristin), telithromycin, vasopressin receptor antagonists (eg, conivaptan), verapamil, or voriconazole because they may increase the risk of muscle or kidney problems
• Bosentan, carbamazepine, rifampin, or St. John's wort because they may decrease Zocor 's effectiveness
• Anticoagulants (eg, warfarin), digoxin, macrolide immunosuppressants (eg, tacrolimus), or spironolactone because the risk of their side effects may be increased by Zocor

This may not be a complete list of al l interactions that may occur. Ask your health care provider if Zocor may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.