Sporanox Solution

Sporanox Solution is used for:

Treating fungal infections. It may also be used for other conditions as determined by your doctor.

Sporanox Solution is an azole antifungal. It kills sensitive fungi by interfering with the formation of the fungal cell membrane.

Do NOT use Sporanox Solution if:

• you are allergic to any ingredient in Sporanox Solution
• you are taking an aldosterone blocker (eg, eplerenone), alprazolam, astemizole, cisapride, conivaptan, dofetilide, an ergot alkaloid (eg, ergotamine), certain HMG-CoA reductase inhibitors (eg, lovastatin, simvastatin), levacetylmethadol (levomethadyl), midazolam, nevirapine, nisoldipine, pimozide, a quinazoline (eg, alfuzosin), quinidine, rifabutin, rifampin, terfenadine, triazolam, or certain 5-HT receptor agonists (eg, eletriptan)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Sporanox Solution:

Some medical conditions may interact with Sporanox Solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have HIV infection, a weakened immune system, low white blood cell levels, cystic fibrosis, kidney or liver problems, heart problems (eg, congestive heart failure, irregular heartbeat, heat valve problems), lung or breathing problems (eg, chronic obstructive pulmonary disease [COPD]), low stomach acid (eg, hypochlorhydria), nerve problems, or problems with swelling
• if you have had serious liver problems caused by Sporanox Solution

Some MEDICINES MAY INTERACT with Sporanox Solution. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Many prescription and nonprescription medicines (eg, used for infections, HIV, seizures, anxiety, sleep, heartburn, diabetes, high cholesterol, heart problems, high blood pressure, allergies, irregular heartbeat, pain, blood thinning, asthma, migraines, mood or mental problems, cancer, prostate problems, immune system suppression, erectile dysfunction, urinary problems, or contraception [birth control]), multivitamin products, and herbal or dietary supplements may interact with Sporanox Solution, increasing the risk of serious side effects
• Nevirapine, rifabutin, or rifampin because they may decrease Sporanox Solution's effectiveness
• Astemizole, cisapride, dofetilide, levacetymethadol (levomethadyl), nisoldipine, pimozide, quinidine, or terfenadine because the risk of severe heart effects may be increased
• Alprazolam, midazolam, or triazolam because their actions and the risk of their side effects may be increased by Sporanox Solution, resulting in increased risk of sedation and breathing difficulties
• Aldosterone blockers (eg, eplerenone), conivaptan, ergot alkaloids (eg, ergotamin e), certain HMG-CoA reductase inhibitors (eg, lovastatin, simvastatin), quinazolines (eg, alfuzosin) or 5-HT receptor agonists (eg, eletriptan) because the risk of their side effects may be increased by Sporanox Solution

This may not be a complete list of all interactions that may occur. Ask your health care provider if Sporanox Solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.