Lariam

Lariam is used for:

Treating or preventing malaria.

Lariam is an antimalarial agent. How it works to kill sensitive malaria parasites is not known.

Do NOT use Lariam if:

• you are allergic to any ingredient in Lariam or similar medicines (eg, quinine, quinidine)
• you do not already have malaria and you currently have depression, a recent history of mental illness (eg, anxiety disorder, depression, psychosis, schizophrenia) or a history of seizures
• you are taking halofantrine

Contact your doctor or health care provider right away if any of these apply to you.

Before using Lariam :

Some medical conditions may interact with Lariam . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines (especially quinine or quinidine), foods, or other substances
• if you have a history of seizures, heart disease, liver problems, or mental or emotional disorders (eg, depression)
• if you are taking medicine for diabetes (eg, glyburide) or an anticoagulant (eg, warfarin)

Some MEDICINES MAY INTERACT with Lariam . Tell your health care provider if you are taking any other medicines, especially any of the following:

• Beta-blockers (eg, propranolol), chloroquine, dofetilide, halofantrine, hydroxychloroquine, paliperidone, quinidine, quinine, or ziprasidone because the risk of heart problems (eg, irregular heartbeat) and seizures may be increased
• Anticoagulants (eg, warfarin) because the risk of bleeding may be increased
• Oral live vaccines because the effectiveness of the vaccine may be decreased. Oral live vaccines should be completed at least 3 days before the first dose of Lariam .
• Anticonvulsants (eg, valproic acid, carbamazapine, phenobarbital, phenytoin) because their effectiveness may be decreased by Lariam

This may not be a complete list of all interactions that may occur. Ask your health care provider if Lariam may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine