Kaletra Solution

Kaletra Solution is used for:

Treating HIV infection. It is used along with other medicines for HIV.

Kaletra Solution is a combination of 2 HIV protease inhibitors. It works by stopping the HIV virus from multiplying.

Do NOT use Kaletra Solution if:

• you are allergic to any ingredient in Kaletra Solution
• you are taking alfuzosin, amiodarone, astemizole, bepridil, certain HMG-CoA reductase inhibitors (eg, lovastatin, simvastatin), cisapride, conivaptan, disulfiram, eletriptan, an ergot derivative (eg, ergotamine, methylergonovine), flecainide, meperidine, metronidazole, midazolam, pimozide, propafenone, quinidine, rifampin, St. John's wort, terfenadine, tipranavir, or triazolam

Contact your doctor or health care provider right away if any of these apply to you.

Before using Kaletra Solution:

Some medical conditions may interact with Kaletra Solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have hepatitis, liver problems, or abnormal liver function tests
• if you have pancreas problems (eg, pancreatitis), diabetes or high blood sugar (hyperglycemia), high cholesterol or triglyceride levels, or hemophilia or another bleeding disorder
• if you have a history of alcohol abuse
• if you take metronidazole or disulfiram
• if you have a history of heart problems (eg, heart failure, conduction abnormalities) or heart blood vessel problems
• if you take another HIV protease inhibitor (eg, atazanavir, tipranavir)

Some MEDICINES MAY INTERACT with Kaletra Solution. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Amiodarone, astemizole, bepridil, cisapride, flecainide, meperidine, pimozide, propafenone, quinidine, or terfenadine because serious side effects such as seizures, blood problems, or heart problems (eg, irregular heartbeat) may occur
• Midazolam or triazolam because serious side effects such as prolonged sedation or breathing problems may occur
• Ergot derivatives (eg, ergotamine, methylergonovine) because serious blood flow problems may occur
• Rifampin because it may decrease Kaletra Solution's effectiveness
• Alfuzosin, certain HMG-CoA reductase inhibitors (eg, lovastatin, simvastatin), conivaptan, or eletriptan because the risk of their side effects may be increased by Kaletra Solution
• Disulfiram or metronidazole because severe nausea and vomiting may occur
• Many prescription and nonprescription medicines (eg, used for infections, HIV, inflammation, allergic reactions, breathing problems, pain, birth control, blood thinning, cancer, irregular heartbeat, other heart problems, high blood pressure, high cholesterol, immune suppression, erectile dysfunction, seizures, sleep disorders, depression, other mood or mental problems), multivitamin products, and herbal or dietary supplements (eg, herbal teas, coenzyme Q10, garlic, ginseng, ginkgo, St. John's wort) because they may interact with Kaletra Solution, increasing the risk of side effects

This may not be a complete list of all interactions that may occur. Ask your health care provider if Kaletra Solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.