Emend

Emend is used for:

Preventing nausea and vomiting associated with certain types of cancer medicines (chemotherapy). It is used in combination with other medicines. It is also used to prevent nausea and vomiting after surgery. It may also be used for other conditions as determined by your doctor.

Emend is an antiemetic. It works by blocking certain substances in the brain, which helps to prevent nausea and vomiting.

Do NOT use Emend if:

• you are allergic to any ingredient in Emend
• you are taking astemizole, cisapride, pimozide, or terfenadine

Contact your doctor or health care provider right away if any of these apply to you.

Before using Emend :

Some medical conditions may interact with Emend . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have liver problems
• if you currently have nausea or vomiting

Some MEDICINES MAY INTERACT with Emend . Tell your health care provider if you are taking any other medicines, especially any of the following:

• Azole antifungals (eg, ketoconazole), diltiazem, HIV protease inhibitors (eg, ritonavir), macrolide antibiotics (eg, clarithromycin), nefazodone, or troleandomycin because they may increase the risk of Emend 's side effects
• Carbamazepine or rifampin because they may decrease Emend 's effectiveness
• Astemizole, benzodiazepines (eg, alprazolam), cisapride, corticosteroids (eg, dexamethasone), ifosfamide, narcotic pain medicines (eg, fentanyl), pimozide, terfenadine, vinblastine, or vincristine because the risk of their side effects may be increased by Emend
• Anticoagulants (eg, warfarin), hormonal contraceptives (eg, birth control pills), paroxetine, phenytoin, or tolbutamide because their effectiveness may be decreased by Emend

This may not be a complete list of all interactions that may occur. Ask your health care provider if Emend may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.