Eldepryl

Eldepryl is used for:

Treating Parkinson disease. Eldepryl is taken with levodopa/carbidopa.

Eldepryl is a monoamine oxidase (MAO) inhibitor. It works by prolonging the anti-Parkinson activity of levodopa, which may help to slow the progression of Parkinson disease. Selegiline has no anti-Parkinson effects of its own and must always be given in combination with levodopa/carbidopa.

Do NOT use Eldepryl if:

• you are allergic to any ingredient in Eldepryl
• you have schizophrenia
• you are taking an anorexiant (eg, phentermine), apraclonidine, brimonidine, bupropion, buspirone, carbamazepine, cyclobenzaprine, dextromethorphan, entacapone, an herbal product (eg, ma huang), indoramin, meperidine, nefazodone, a norepinephrine reuptake inhibitor (eg, atomoxetine), papaverine, a serotonin norepinephrine reuptake inhibitor (eg, venlafaxine), sibutramine, a selective serotonin reuptake inhibitor (SSRI) antidepressant (eg, fluoxetine, citalopram), a sympathomimetic (eg, ephedrine, methylphenidate), a tetracyclic antidepressant (eg, trazodone), tolcapone, tramadol, a tricyclic antidepressant (eg, amitriptyline, doxepin), or a "triptan" (eg, sumatriptan, zolmitriptan)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Eldepryl :

Some medical conditions may interact with Eldepryl . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have a mental disorder (eg, psychosis), tardive dyskinesia (twitching of the face and tongue, involuntary movements of the arms and legs), or an ulcer

Some MEDICINES MAY INTERACT with Eldepryl . Tell your health care provider if you are taking any other medicines, especially any of the following:

• Apraclonidine or ethanol because the actions and side effects of Eldepryl may be increased
• Anorexiants (eg, phentermine), bupropion, carbamazepine, cyclobenzaprine, dextromethorphan, insulin, levodopa, meglitinide antidiabetics (eg, repaglinide), meperidine, nefazodone, norepinephrine reuptake inhibitors (eg, atomoxetine), propoxyphene, serotonin norepinephrine reuptake inhibitors (eg, venlafaxine), SSRI antidepressants (eg, fluoxetine), sibutramine, sulfonylureas (eg, glyburide), sumatriptan, sympathomimetics (eg, ephedrine, methylphenidate), tetracyclic antidepressants (eg, trazodone), tramadol, tricyclic antidepressants (eg, amitriptyline), or tryptophan because the actions and side effects of these medicines may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Eldepryl may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.