Diabinese Generic Name: Chlorpropamide Brand Name: Diabinese
Diabinese is used for:Treating type 2 diabetes in patients who cannot control blood sugar levels by diet and exercise alone. It is used along with diet and exercise. It may be used alone or with other antidiabetic medicines. Diabinese is a sulfonylurea antidiabetic medicine. It causes the pancreas to release insulin, which helps to lower blood sugar. Do NOT use Diabinese if:- you are allergic to any ingredient in Diabinese
- you have certain severe problems associated with diabetes (eg, diabetic ketoacidosis, diabetic coma)
- you have type 1 diabetes
- you have severe liver, kidney, thyroid, or endocrine problems
- you have moderate to severe burns, or very high blood acid levels (acidosis)
- you are pregnant and are within 1 month of the expected delivery date
Contact your doctor or health care provider right away if any of these apply to you. Before using Diabinese :Some medical conditions may interact with Diabinese . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you: - if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have had a severe allergic reaction (eg, a severe rash, hives, breathing difficulties, dizziness) to any other sulfonamide medicine, such as acetazolamide, celecoxib, certain diuretics (eg, hydrochlorothiazide), glipizide, probenecid, sulfamethoxazole, valdecoxib, or zonisamide
- if you have a history of liver, kidney, thyroid, or heart problems
- if you have stomach or bowel problems (eg, stomach or bowel blockage, stomach paralysis), drink alcohol, or have had poor nutrition
- if you have very poor health, a high fever, a severe infection, severe diarrhea, or high blood acid levels, or have had a severe injury
- if you have a history of certain blood problems (eg, porphyria), certain hormonal problems (eg, adrenal or pituitary problems, syndrome of inappropriate secretion of antidiuretic hormone [SIADH]), or low blood sodium levels
- if you will be having surgery
Some MEDICINES MAY INTERACT with Diabinese . Tell your health care provider if you are taking any other medicines, especially any of the following: - Beta-blockers (eg, propranolol) because the risk of low blood sugar may be increased. They may also hide certain signs of low blood sugar and make it more difficult to notice
- Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril), anticoagulants (eg, warfarin), azole antifungals (eg, miconazole, ketoconazole), chloramphenicol, clofibrate, fenfluramine insulin, monoamine oxidase (MAO) inhibitors (eg, phenelzine), nonsteroidal anti-inflammatory medicines (NSAIDs) (eg, ibuprofen), phenylbutazone, probenecid, quinolone antibiotics (eg, ciprofloxacin), salicylates (eg, asp
irin), sulfonamides (eg, sulfamethoxazole), or urinary acidifiers (eg, ammonium chloride) because the risk of low blood sugar may be increased
- Calcium channel blockers (eg, diltiazem), corticosteroids (eg, prednisone), decongestants (eg, pseudoephedrine), diazoxide, diuretics (eg, furosemide, hydrochlorothiazide), estrogens, hormonal contraceptives (eg, birth control pills), isoniazid, niacin, phenothiazines (eg, promethazine), phenytoin, rifamycins (eg, rifampin), sympathomimetics (eg, albuterol, epinephrine, terbutaline), or thyroid supplements (eg, levothyroxine) because they may decrease Diabinese 's effectiveness, resulting in high blood sugar
- Gemfibrozil because blood sugar may be increased or decreased
- Barbiturates (eg, phenobarbital) because the risk of their side effects may be increased by Diabinese
This may not be a complete list of all interactions that may occur. Ask your health care provider if Diabinese may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
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