Desyrel

Desyrel is used for:

Treating depression. It may also be used for relief of an anxiety disorder (eg, sleeplessness, tension), chronic pain. It may also be used for other conditions as determined by your doctor.

Desyrel is a tetracyclic antidepressant. It is thought to increase the activity of one of the brain chemicals (serotonin), which helps elevate mood.

Do NOT use Desyrel if:

• you are allergic to any ingredient in Desyrel or nefazodone
• you are taking sodium oxybate (GHB)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Desyrel :

Some medical conditions may interact with Desyrel . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have heart disease including irregular heartbeat or have had a heart attack
• if you have a history of depression or suicidal tendencies
• if you are scheduled to have surgery
• if you consume alcoholic beverages

Some MEDICINES MAY INTERACT with Desyrel . Tell your health care provider if you are taking any other medicines, especially any of the following:

• Carbamazepine, ethanol, ginkgo biloba, HIV protease inhibitors (eg, ritonavir), phenothiazines (eg, thioridazine), or serotonin reuptake inhibitors (eg, fluoxetine) because side effects, such as increased drowsiness or blurred vision, may occur
• Buspirone, carbamazepine, digoxin, hydantoins (eg, phenytoin), itraconazole, ketoconazole, nefazodone, serotonin reuptake inhibitors (eg, fluoxetine), or sodium oxybate (GHB) because the risk of their side effects may be increased by Desyrel
• Anticoagulants (eg, warfarin) because they may decrease Desyrel 's effectiveness. Your doctor may want to adjust your dose while taking Desyrel

This may not be a complete list of all interactions that may occur. Ask your health care provider if Desyrel may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.