Crixivan

Crixivan is used for:

Treating HIV infection in some patients when used in combination with certain other medicines.

Crixivan is an HIV protease inhibitor. It works by slowing the growth of HIV, the virus that causes AIDS.

Do NOT use Crixivan if:

• you are allergic to any ingredient in Crixivan
• you are taking alfuzosin, amiodarone, astemizole, atazanavir, certain benzodiazepines (eg, alprazolam, midazolam, triazolam), certain HMG-CoA reductase inhibitors (eg, lovastatin, simvastatin), cisapride, an ergot derivative (eg, ergonovine, ergotamine), erythromycin, pimozide, a proton pump inhibitor (eg, omeprazole), rifampin, a serotonin 5-HT₁ receptor antagonist (eg, eletriptan, sumatriptan), St. John's wort, or terfenadine

Contact your doctor or health care provider right away if any of these apply to you.

Before using Crixivan :

Some medical conditions may interact with Crixivan . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have cirrhosis, liver or kidney problems, diabetes, high blood sugar, high cholesterol, kidney stones, urinary problems (eg, white blood cells in the urine), or blood problems (eg, hemophilia hemolytic anemia)

Some MEDICINES MAY INTERACT with Crixivan . Tell your health care provider if you are taking any other medicines, especially any of the following:

• Amiodarone, astemizole, certain benzodiazepines (eg, alprazolam, midazolam,triazolam), cisapride, ergot alkaloids (eg, ergotamine), erythromycin, pimozide, and terfenadine because serious side effects such as increased or prolonged sedation or breathing problems, seizures, blood vessel problems, or heart problems (eg, irregular heartbeat) may occur
• Atazanavir because it may increase the risk of a buildup of bilirubin in the blood
• Proton pump inhibitors (eg, omeprazole), rifampin, or St. John's wort because they may decrease Crixivan 's effectiveness
• Alfuzosin, certain HMG-CoA reductase inhibitors (eg, lovastatin, simvastatin), conivaptan, ranolazine, serotonin 5-HT1 antagonists (eg, eletriptan, sumatriptan) because the risk of their side effects may be increased by Crixivan
• Many prescription and nonprescription medicines (eg, used for infections, inflammation, aches and pains, high blood pressure, high cholesterol, heart problems, anxiety, mood or mental problems, depression, sinus problems, erectile dysfunction, seizures, other medicines used for HIV infection), multivitamin products, and herbal or dietary supplements (eg, herbal teas, coenzyme Q10, garlic, ginseng, ginkgo) may interact with Crixivan , increasing the risk of side effects

This may not be a complete list of all interactions that may occur. Ask your health care provider if Crixivan may interact with other medicines that you take. Check with your health care provider before y ou start, stop, or change the dose of any medicine.