Compazine

Generic Name: Prochlorperazine
Brand Name: Compazine

Compazine is used for:

Controlling severe nausea and vomiting and treating schizophrenia. It is also used for the short-term (4 weeks) treatment of generalized nonpsychotic anxiety. It may also be used for other conditions as determined by your doctor.

Compazine is a phenothiazine. It works by blocking a certain chemical (dopamine) in the brain.

Do NOT use Compazine if:

• you are allergic to any ingredient in Compazine or similar medicines
• you are taking large amounts of central nervous system depressants (eg, alcohol, barbiturates, narcotics)
• you are taking astemizole, cisapride, or terfenadine
• you have severe central nervous system depression

Contact your doctor or health care provider right away if any of these apply to you.

Before using Compazine :

Some medical conditions may interact with Compazine . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have a history of heart disease, central nervous system depression, blood problems, liver problems, low blood pressure, increased pressure in the eye, neuroleptic malignant syndrome, tardive dyskinesia, bone marrow problems, unusual muscle movements, Parkinson disease, a predisposition to glaucoma, Reye syndrome, prostate problems, or seizures, or you have alcoholism

Some MEDICINES MAY INTERACT with Compazine . Tell your health care provider if you are taking any other medicines, especially any of the following:

• Anticholinergics (eg, diphenhydramine, oxybutynin, scopolamine) or lithium because they may decrease Compazine 's effectiveness
• Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril), anticholinergics (eg, diphenhydramine, oxybutynin, scopolamine), general anesthetics (eg, thiopental), haloperidol, methyldopa, or tricyclic antidepressants (eg, amitriptyline) because the risk of side effects, such as seizures, may be increased
• ACE inhibitors (eg, enalapril), anticholinergics (eg, diphenhydramine, oxybutynin, scopolamine), astemizole, cisapride, dofetilide, haloperidol, hydantoins (eg, phenytoin), methyldopa, metrizamide, naltrexone, polypeptide antibiotics (eg, actinomycin), serotonin receptor antagonist antiemetics (eg, ondansetron), terfenadine, tramadol, trazodone, or tricyclic antidepressants (eg, amitriptyline) because the risk of their side effects may be increased by Compazine
• Bromocriptine, guanethidine, levodopa, or pergolide because their effectiveness may be decreased by Compazine
• Lithium because unexpected toxic effects may occur

This may not be a complete list of all interactions that may occur. Ask your health care provider if Compazine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.< /p>