Clinoril

Clinoril is used for:

Treating rheumatoid arthritis, osteoarthritis, or ankylosing spondylitis. It is used to treat gout or certain types of bursitis and tendonitis. It may also be used for other conditions as determined by your doctor.

Clinoril is an NSAID. Exactly how it works is not known. It may block certain substances in the body that are linked to inflammation. NSAIDs treat the symptoms of pain and inflammation. They do not treat the disease that causes those symptoms.

Do NOT use Clinoril if:

• you are allergic to any ingredient in Clinoril
• you have had a severe allergic reaction (eg, severe rash, hives, trouble breathing, growths in the nose, dizziness) to aspirin or an NSAID (eg, ibuprofen, celecoxib)
• you have recently had or will be having bypass heart surgery
• you are also taking another NSAID (eg, ibuprofen)
• you are in the last 3 months of pregnancy

Contact your doctor or health care provider right away if any of these apply to you.

Before using Clinoril :

Some medical conditions may interact with Clinoril . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have a history of kidney or liver disease, diabetes, stomach or bowel problems (eg, bleeding, perforation, ulcers), or inflammation of the pancreas
• if you have a history of swelling or fluid buildup, kidney stones, asthma, growths in the nose (nasal polyps), or mouth inflammation
• if you have high blood pressure, a blood disorder, bleeding or clotting problems, heart problems (eg, heart failure), lupus or other connective tissue disease, or blood vessel disease, or if you are at risk for any of these diseases
• if you have poor health, dehydration or low fluid volume, or low blood sodium levels, if you drink alcohol, or if you have a history of alcohol abuse

Some MEDICINES MAY INTERACT with Clinoril . Tell your health care provider if you are taking any other medicines, especially any of the following:

• Anticoagulants (eg, warfarin), aspirin, corticosteroids (eg, prednisone), heparin, other NSAIDs (eg, ibuprofen), or selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine) because the risk of stomach bleeding may be increased
• Probenecid because it may increase the risk of Clinoril 's side effects
• Diflunisal or dimethyl sulfoxide (DMSO) because they may decrease Clinoril 's effectiveness
• Cyclosporine, lithium, methotrexate, quinolones (eg, ciprofloxacin), or sulfonylureas (eg, glipizide) because the risk of their side effects may be increased by Clinoril
• Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril), angiotensin receptor blockers (eg, losartan) , or diuretics (eg, furosemide, hydrochlorothiazide) because their effectiveness may be decreased by Clinoril

This may not be a complete list of all interactions that may occur. Ask your health care provider if Clinoril may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.